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Thoracic Imaging Case of the Week:  August 20-August 27, 2010
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64-year-old woman with clinical suspicion of an atrial mass on the basis of recent echosonography
What are the pertinent findings on the cardiac MRI? What is your leading diagnosis?


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Answer to Case of the Week: Aug 13-Aug 20, 2010

Rule-out lung cancer

Does the radiographic opacity in question represent a primary lung cancer? If not, why and what would be an alternative explanation?


Radiologic Findings PA (Fig. A) and lateral (Fig. B) chest radiographs demonstrate evidence of a remote median sternotomy. The cardiomediastinal silhouette is enlarged and vascular redistribution is evident. A right-sided pleural effusion is present which partially silhouettes the ipsilateral diaphragm and blunts the posterior and lateral sulcus. An ovoid radio-opacity is present in the right hemithorax. The long axis of this opacity parallels the long axis of the horizontal fissure. The opacity also changes its morphology from one orthogonal view to the next, relatively foreshortened on the frontal exam (Fig. A) and becoming more elongated on the lateral exam (Fig. B). Both of the latter findings confirm the lesion in question is pleural-based and not parenchymal-based. Also note the absence of air-bronchograms.

Diagnosis: Interlobar Pseudotumor; Cardiac Decompensation

Differential Diagnosis

  • Hematoma
  • Pleural Metastases
  • Primary Pleural Neoplasms

Discussion

Interlobar Pseudotumor is known by various terms including interlobar fluid, interfissural fluid, pseudotumor, phantom tumor, and vanishing tumor. For unknown reasons, the pleural effusion associated with heart failure may occasionally localize in one of the interlobar fissures simulating a mass or true tumor. Although this may occur in any standard or accessory fissure, there is a predilection for such to occur in the horizontal fissure of the right lung (78% cases). Interlobar fluid collections may also be seen less frequently in the setting of renal failure and hepatic hydrothorax. An important point to remember is that these fluid collections are simply “localized” and not “loculated” within the fissure. A point easily illustrated with dependent decubitus radiographs which can be acquired in problematic or questionable cases.

Clinical Findings

The clinical findings are related to the underlying responsible disease process, most often heart failure, and not the pleural effusion itself.

Imaging Findings

  • Homogeneous ovoid opacity oriented along long axis of fissure (Fig A and B)
  • Evidence of ipsilateral pleural fluid (Fig A and B)
  • Absence of air-bronchograms (Fig A and B)
  • Morphology changes from one orthogonal view to the next (Fig A and B)
  • Mobile with decubitus positioning
  • Invariably additional radiographic evidence of concomitant or resolving heart failure (Fig A and B)

Treatment

  • Directed toward the underlying disease process

Prognosis

  • Related to the underlying disease process
  • Interlobar fluid collections tend to resorb spontaneously, hence the alternate designations “phantom tumor” and “vanishing tumor”

Selected Readings

  1. Fraser RS, Müller NL, Colman N, Paré PD. Pleural Abnormalities. In: Fraser and Pare’s Diagnosis of Diseases of the Chest, 4th ed. W.B. Saunders Company, Philadelphia 1999; 579-581.
  2. Haus BM, Stark P, Shofer SL, Kuschner WG. Massive Pulmonary Pseudotumor. Chest 2003; 124(2):758-760.

Residents Submitting Correct Diagnosis - Case of the Week
Radiology
Medicine/Pulmonary
VCU Resident
  • Jeremy Camden
  • Brian Deuell
  • Jonathan Ha
  • Kathryn Jones
  • Adam McLaurin
  • Aaron Nordgren
  • Kenny Uy
  • Matt Walsworth
  • Laveena Chhatwani
  • Keith Goulet
  • Jared Shipley
    Others
  • Pankaj AgarwalIndia
  • Aliasghar AghajaniIslamic Republic of Iran
  • Dr.ajay AgrawalIndia
  • Amr AjlanCanada
  • Gitanjali BajajIndia
  • Jaiger CIndia
  • Shashidharreddy EtikaalaIndia
  • Kirti GehlotIndia
  • Rajesh GothiIndia
  • Ramazan JafariIslamic Republic of Iran
  • Gita KarandeIndia
  • Nicole KelleherUnited States of America
  • Asad KhanPakistan
  • John KirkhamUnited States of America
  • PRAGATI KUMARUnited States of America
  • Abirami MahadevanIndia
  • Umapathi MaheshIndia
  • Matt MorganUnited States of America
  • Shanaree MuzinichUnited States of America
  • Wael NemattallaEgypt
  • Robert PalmerUnited States of America
  • Rajesh SIndia
  • Dipal ShahIndia
  • Tripura SharmaIndia
  • Sumat SharmaIndia
  • Garrick ShermanUnited States of America
  • Nitin SinghCanada
  • Abraham SokolPanama
  • Chad St. GermainUnited States of America
  • Brian TrottaUnited States of America
  • Roja TummaIndia
  • Yutthaphan WannasophaThailand

    Past Winners for Thoracic Imaging Case of the Week:

    2009-2010 Nicole Kelleher, M.D. (VCU Radiology),Keith Goulet, M.D. (VCU Medicine/Pulmonary), John Kirkham, M.D. ( Outside Institutions)


    Previous Thoracic Imaging Cases of the Week



    Archived Thoracic Imaging Cases


    Disclaimer: This information is intended solely for resident review of presented cases which may or may not be pathologically proven. Information is derived from a number of published sources of varying reliability and does not represent original research from the institution. It is not intended to be comprehensive and should therefore not substitute for careful review of the literature.